Eukaryotic Chromosome Structure Answer Key
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Chromosomes are the primary organizational unit of the nucleus. They are the fundamental building blocks of the nucleus. Chromosomes are dynamic, being subject to many different types of regulation. Chromosome structure and function are closely related. Chromosomes are subject to regulation through transcription, replication, repair, and recombination.
Nucleosomes are connected by unstructured linker DNA, which allows the assembly of chromatin fibers. The result is a 30-nm fiber with periodic structures like beads on a string. This fiber then folds back on itself to form the 3-dimensional chromosome.
During development, the number of chromosomes increases and decreases, while the amount of DNA within a chromosome remains constant. As many as seven chromosomes can be found in a single nucleus of amphibian oocytes. For this reason, chromosomes are often referred to by their number, such as the chromosome 1, chromosome 2, or chromosome 3.
Transcription and replication are the primary processes responsible for regulating the number of genes that are expressed and replicated in the cell. Chromosomes can be replicated in several ways. One way is to replicate a large segment of a chromosome, then anchor one end of the replicated DNA to the nuclear membrane and let the cell divide in half. The other way is to replicate the entire chromosome and then repeatedly move it to new locations within the nucleus.
Each turn of the fiber is called a helical repeat. A nucleosome has two turns, and the fiber has six. The organization of the chromatin fiber is a complex and highly regulated process that not only provides the necessary physical stucture, but also explains how the chromosomes can be moved to different locations within the nucleus during cell division.
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